By James A. Hall
Breast melanoma is the commonest malignancy present in girls. fundamental care services for girls, together with obstetricians and gynecologists, are frequently the 1st to notice abnormalities of their sufferers' healthiness and are frequently the resource that their sufferers belief such a lot in terms of clinical concerns. they have to be familiar with breast care whether the sufferer is below the care of a breast health practitioner, clinical oncologist, or radiation oncologist. a transparent, concise, cutting-edge source, An Atlas of Breast ailment offers simple wisdom on anatomy, pathology, and the function of the first care supplier in breast care.
Filled with succinct colour algorithms, charts, graphs, and figures, the Atlas offers complicated details briefly, lucid, and simply comprehensible codecs that may be speedy grasped through the reader. a number of tables, illustrative mammograms, and key aspect summaries, drawn from the authors' medical perform supplement the textual content. colour photomicrographs of pertinent standard histology and pathology additionally upload visible effect. those gains and extra make An Atlas of Breast affliction a pragmatic refresher and medical reference for fundamental care services, obstetricians, and gynecologists handling the final wellbeing and fitness of sufferers with breast disorder.
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Additional info for An Atlas of Breast Disease (The Encyclopedia of Visual Medicine)
P. Jennewein. K. Janke. C. Heutler. E. Klimpgen. N. Romani. and G. Schuler. 1996. High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-IO. J. Exp. Med. 184:741-746. 18. Cella. • D. Scheidegger. K. Palmer-Lehmann. P. Lane. A. Lanzavecchia. and O. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.
This notion correlates with results from transplantation studies: A direct release of allogeneic DC from the tissue into the blood was observed after allografting ''l·2o, and may as well occur in healthy, untreated individuals. This provides an explanation for the appearance of mature DC in the blood. Importantly, because of its lack in afferent lymphatics, the spleen recruits DC from the blood (Fig. 2). DC may develop from monocytes as a result of prolonged purification. Accordingly, culture of monocytes leads to a transient peak of accessory activity and DC morphology after 24 hours21.
W. J. Swiggard, C. Heutler, M. Peng, A. M. C. Nussenzweig, The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375:151 (1995). 5. D. Vremec, M. Zorbas, R. J. F. Ardavin, L. Wu, and K. Shortman. The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells, J. ExP. Med. 176:47 (1992). 6. P. Matzinger and S. Guerder, Does T-cell tolerance require a dedicated antigen-presenting cell?
An Atlas of Breast Disease (The Encyclopedia of Visual Medicine) by James A. Hall