Download e-book for iPad: Aging and Life-Prolonging Processes by Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)

By Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)

ISBN-10: 3709186498

ISBN-13: 9783709186497

ISBN-10: 370918651X

ISBN-13: 9783709186510

There is an Inca incantation which said stated approximately: "Lord, supply me religious peace in order that i will acquiesce to what i can't switch, provide me braveness in order that i will switch what i will switch, and provides me knowledge in order that i will be able to distinguish one from the opposite. " evidently, this incantation may be frequently repeated by means of any gerontologist, because it is especially tough to differentiate getting older from the procedures which complement the organism's viability, getting older from illnesses, and the mechanisms of getting older in a number of species of animals. in keeping with N. surprise, who compiled a beneficial bibliography of the works on getting older, greater than 43,000 works on gerontology were released within the final decade. Why can we proceed to disagree with each other and carry that an important mechanisms are nonetheless principally unknown to us regardless of that movement of data and a huge variety of evidence? what's it that we don't understand? may or not it's that we don't recognize the only sacramental truth that can clarify every little thing, similar to the hormone of getting older, the programmed triggering of a suicide gene, the looks of a different poisonous agent within the axoplasmic circulate of drugs, etc? Goethe as soon as wrote scientist typically holds sure components, yet regrettably he lacks their sacred link.

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This consolidation of vitauct explains the steady increase in the mammalian life span. This increase is especially great among primates. The occurrences in the post-reproductive period cannot be genetically consolidated. They are thus irreversible in evolution. The forms of regulation and adaptation were perfected as the biological organization became complicated in the course of evolution. At the same time, definite aging mechanisms changed and were transformed. The mechanisms of vitauct and aging qualitatively changed as they came under central, neurohumoral control.

According to Vernadakis (1975), the activity of acetylcholinesterase (which is specific for neurons) decreases, while that of butyrylcholinesterase localized in the glia cells increases in old age. The number of glia cells in various brain structures changes differently in old age. For instance, the number of these cells in the grey matter of the brain increases, but it decreases in its white matter (Sturrock, 1977). When the number of glia cells increases, the blood supply of the neurons may worsen, their position with respect to the capillaries may alter, and the interneuronal relationships may change substantially.

81). Mortality due to ischemic heart disease sharply increases among men as early as the age of 35-44. This shows that the pathology of the cardiovascular system originates and rapidly develops not only among elderly and old persons, but also among younger persons. In this respect, it should be noted that the given pathology, i. e. ischemic heart disease, myocardial infarction and arterial hypertension, occurs more and more frequently among young persons, although it is true that the average life span is increasing.

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Aging and Life-Prolonging Processes by Prof. Dr. Vladimir Veniaminovich Frolkis (auth.)


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